Tannic acid: A Green Catalyst for the Eco-friendly Synthesis of 2,3-dihydroquinazolin-4(1H)-ones under Solvent Free Conditions

Document Type: Research Paper

Authors

1 Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan, Iran

2 Department of Chemistry, Faculty of Sciences, University of Sistan and Baluchestan, Zahedan,Iran

Abstract

A new, facile, cost effective, and eco-friendly protocol is reported for the synthesis of 2,3-
dihydroquinazoline-4-(1H)-ones exploring tannic acid as a novel, inexpensive, and
biodegradable catalyst. A variety of dihydroquinazolins were prepared from aromatic aldehydes
and anthranilamide using catalytic amount of tannic acid under solvent free conditions.
Operational simplicity, high yield, and high atom-economy are the important features of this
protocol.

Keywords