Nano SnCl2-SiO2 Catalyzed Facile Synthesis of Aryloylamido Coumarins Derivatives

Document Type: Research Paper

Author

Department of Chemistry, Mahshahr Branch, Islamic Azad University, Mahshahr, Iran

Abstract

A highly efficient and general method for the synthesis of aryloylamido coumarins
derivatives by a three-component condensation of 4-hydroxycoumarin or 4-hydroxy-6-
methylpyran-1-one, aryl glyoxals and benzamide in the presence of nano silica supported tin
(II) chloride as a heterogeneous catalyst is established. In this method, SnCl2/nano SiO2 was
used as green and reusable catalyst. Excellent yields, short reaction times, simple workup,
and inexpensiveness and commercially availability of the catalyst are the advantages of this
method.

Keywords