Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan,Iran
Department of Chemistry, Faculty of Science, University of Sistan and Baluchestan, Zahedan, Iran
An efficient sodium bismuthate (NaBiO3) synthesis of biologically active spiro[4H-pyran]
derivatives has been accomplished via one-pot three-condensation of isatin/acenaphthequinone, malononitrile and different reagents including 1,3-dicrbonyl compounds, α-naphthol and 4-hydroxycumarin under solvent-free conditions. The notable advantages of the present procedure are: eco-friendly, environmentally benign nature,low-cost and non-toxic catalyst, simplicity of operation with no necessity of chromatographic
purification steps, short reaction times, good to high yields and solvent-free conditions.