Structure Exploring, IR and UV Spectroscopic Properties of Pomalidomide as a Second-generation of Immunomodulatory Agent

Authors

1 Department of Chemistry, Faculty of science, East Tehran branch, Islamic Azad University, Qiam Dasht, Tehran, Iran

2 Department of Medical Nanotechnology, International Campus, Tehran University of Medical Sciences, Tehran, Iran

3 Department of Biology, Scienceand Research Branch, Islamic Azad University, Tehran, Iran

4 Department of Pharmaceutics,Faculty of Pharmacy,Tehran Universityof Medical Scienses,Tehran, Iran

Abstract

In this article, the optimized geometry, IR and UV spectra, frontier orbital analysis, natural bond
orbital (NBO) analyses, and thermodynamic parameters of pomalidomide were investigated. The
calculated structural parameters and stretching frequencies values are compared with experimental
values of the investigated compound. Also, the relations of the thermodynamic functions vs.
temperatures were fitted by quadratic formulas.


Keywords