H6P2W18O62: A Green and Reusable Catalyst for the One-pot Three-Component Synthesis of Spirooxindoles in Water

Document Type: Research Paper



Wells–Dawson tungsten heteropolyacid (H6P2W18O62) has been applied as an effective
heterogeneous catalyst for one-pot synthesis of spiro[4H-pyran-3,3’-oxindoles] via reaction of
various isatins, malonitrile and 1,3-dicarbonyl compound in water. The corresponding products
were obtained in high yields. The catalysts were easily recycled and reused without loss of their
catalytic activity.