An Efficient Protocol for Synthesis of 2-amino-3cyanopyridine Derivatives using Nano-modified SBA-15

Document Type: Research Paper



Condensation reaction of chalcones with malononitrile and ammonium acetate in the presence of the green nano-modified SBA-15 affords the corresponding 2-amino-3-cyanopyridine derivatives in excellent yield. This approaches claimed to be an environment friendly protocol as it afforded some advantages such as excellent yields and cleaner reaction.