Application of Green Procedure for the Synthesis of Substituted Pyrroles: Multi-component Reaction of Oxalyl Chloride

Document Type: Research Paper

Authors

Abstract

A novel, convenient and efficient approach to synthesis of pyrrole derivatives via the reaction
of primary amines, alkyl propiolates and oxalyl chloride is described. The method offers
several advantages including high yields of products and performing reaction in water as the
solvent. 

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