Caro’sacid-silicagel: An Efficient and Reusable Catalyst for the Synthesis of 2, 4, 5- Trisubstituted Imidazoles under Solvent-free Conditions

Document Type: Research Paper

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Abstract

Caro’s acid-silicagel was found to be a mild and effective catalyst for the one –pot multicomponent condensation of benzyl, aldehydes and ammonium acetate used for synthesis of 2, 4, 5-trisubstituted imidazole derivatives under solvent–free conditions. This catalyst has several advantages such as simple work-up, low cost and reusability.

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